fangmcgee writes "Lab-grown leather apparel could hit the runways in as little as five years—all without harming a hair on a single animal's head, according to Andras Forgacs, co-founder and CEO of Modern Meadow, a Missouri-based startup that's approaching meat-and-leather production from a tissue-bioengineering, rather than farming, point of view. Backed by Breakout Labs, the grant-awarding foundation headed by PayPal co-founder Peter Thiel, Modern Meadow seeks to combine regenerative medicine with three-dimensional printing to synthesize leather and ultimately meat."

When you think of garage-based tech start-ups, hardware makers like Apple or data-manipulators like Google probably spring to mind before biotech, and way before farming. Lewis Weil, though, has for the last several years been perfecting the art of growing seaweed in central Texas, and his Austin Sea Veggies have garnered interest from gourmets and restaurants across the U.S. In large part, that's because seaweed is so useful for industrial purposes, it's getting harder to find eating seaweed these days. Lewis says there's nothing stopping anyone with an interest in aquaculture in emulating his success as an inland ocean farmer, but has some cautions, too -- when small things go wrong, or a record heatwave overcomes humans' puny air conditioning systems, your seaweed harvest can fail just like any other crop. Update: 09/19 16:40 GMT by T : Now with transcript! If video's too slow and linear, click below to read what Lewis had to say.

puddingebola sends this excerpt from an article at ScienceNow: "Scientists have enabled deaf gerbils to hear again — with the help of transplanted cells that develop into nerves that can transmit auditory information from the ears to the brain. The advance, reported today in Nature, could be the basis for a therapy to treat various kinds of hearing loss. ... Rivolta and his colleagues knew that during embryonic development, a handful of proteins, including fibroblast growth factor (FGF) 3 and 10, are required for ears to form. So they exposed human embryonic stem cells to FGF3 and FGF10. Multiple types of cells formed, including precursor inner-ear hair cells, but they were also able to identify and isolate the cells beginning to differentiate into the desired spiral ganglion neurons. Then, they implanted the neuron precursor cells into the ears of gerbils with damaged ear neurons and followed the animals for 10 weeks. The function of the neurons was restored.'"

Mansing writes "Citizens need to evaluate if they are indeed safer for all the 'security precautions' put into place. 'The U.S. Department of Homeland Security has rushed to acquire a new, multibillion-dollar version of the BioWatch system for detecting biological attacks without establishing whether it was needed or would work, according to a new report by a nonpartisan investigative arm of Congress. ... The existing system's repeated false alarms have triggered tense, high-stakes deliberations over whether to order mass evacuations, distribute emergency medicines or shut down major venues.' Is this just more money funneled to U.S. companies, or is this really keeping the U.S. safer? Are the same types of 'security precautions' being instituted in Spain and the UK? Or is this preying on fear a uniquely U.S. phenomenon?"

ananyo writes "In what is likely to be a historic moment in science, ENCODE, the Encyclopedia of DNA Elements, has published 30 papers in Nature, Genome Research and Genome Biology today, assigning some sort of function to roughly 80% of the genome, including more than 70,000 'promoter' regions — the sites, just upstream of genes, where proteins bind to control gene expression — and nearly 400,000 'enhancer' regions that regulate expression of distant genes. The project was designed to pick up where the Human Genome Project left off. Although that massive effort revealed the blueprint of human biology, it quickly became clear that the instruction manual for reading the blueprint was sketchy at best. Researchers could identify in its 3 billion letters many of the regions that code for proteins, but those make up little more than 1% of the genome, contained in around 20,000 genes. ENCODE, which started in 2003, aims to catalog the 'functional' DNA sequences between genes, learn when and in which cells they are active and trace their effects on how the genome is packaged, regulated and read. Nature has set up an ENCODE site with an explorer, that groups the papers by topic, and collects all the papers, which are available free."

Zothecula writes "The Forest Products Laboratory of the US Forest Service has opened a US$1.7 million pilot plant for the production of cellulose nanocrystals (CNC) from wood by-products materials such as wood chips and sawdust. Prepared properly, CNCs are stronger and stiffer than Kevlar or carbon fibers, so that putting CNC into composite materials results in high strength, low weight products. In addition, the cost of CNCs is less than ten percent of the cost of Kevlar fiber or carbon fiber. These qualities have attracted the interest of the military for use in lightweight armor and ballistic glass (CNCs are transparent), as well as companies in the automotive, aerospace, electronics, consumer products, and medical industries."

submeta writes "Researchers at MIT and the University of Pennsylvania have genetically engineered skeletal muscle cells to respond to light. The hope is that this 'bio-integrated' approach may lead to 'highly articulated, flexible robots.' The technique, known as optogenetics, has previously been used to stimulate neurons in worms to fire."

ananyo writes "Tens of thousands of years ago modern humans crossed paths with the group of hominins known as the Neandertals. Researchers now think they also met another, less-known group called the Denisovans. The only trace that we have found, however, is a single finger bone and two teeth, but those fragments have been enough to cradle wisps of Denisovan DNA across thousands of years inside a Siberian cave. Now a team of scientists has been able to reconstruct their entire genome from these meager fragments. The analysis supports the idea that Neandertals and Denisovans were more closely related to one another than either was to modern humans and also suggests new ways that early humans may have spread across the globe." wombatmobile linked to an article that focuses on the new techniques used to sequence the DNA of the bone fragments in question.

Hugh Pickens writes "Thanks to fast-paced television crime shows such as CSI, we have come to regard DNA evidence as incontestable. But BBC reports that David Butler has every right to be cynical about the use of DNA evidence by the police. Butler spent eight months in prison, on remand, facing murder charges after his DNA was allegedly found on the victim. 'I think in the current climate [DNA] has made police lazy,' says Butler. 'It doesn't matter how many times someone like me writes to them, imploring they look at the evidence... they put every hope they had in the DNA result.' The police had accused Butler of murdering a woman, Anne Marie Foy, in 2005 — his DNA sample was on record after he had willingly given it to them as part of an investigation into a burglary at his mother's home some years earlier. But Butler has a rare skin condition, which means he sheds flakes of skin, leaving behind much larger traces of DNA than the average person. Butler worked as a taxi driver, and so it was possible for his DNA to be transferred from his taxi via money or another person, onto the murder victim. The case eventually went to trial and Butler was acquitted after CCTV evidence allegedly placing Butler in the area where the murder took place was disproved. Professor Allan Jamieson, head of the Glasgow-based Forensic Institute, has become a familiar thorn in the side of prosecutors seeking to rely on DNA evidence and has appeared as an expert witness for the defense in several important DNA-centered trials, most notably that of Sean Hoey, who was cleared of carrying out the 1998 Omagh bombing, which killed 29 people. Jamieson's main concern about the growing use of DNA in court cases is that a number of important factors — human error, contamination, simple accident — can suggest guilt where there is none. 'Does anyone realize how easy it is to leave a couple of cells of your DNA somewhere?' says Jamieson. 'You could shake my hand and I could put that hand down hundreds of miles away and leave your cells behind. In many cases, the question is not "Is it my DNA?", but 'How did it get there?"'"

retroworks writes "Rebecca J. Rosen interviews experts in this edition of The Atlantic, to ask about the ethics and wisdom of using cloning, backbreeding, or genome editing. Over 90% of species ever to exist on earth are no more. The article ponders the moral and environmental challenges of humans reintroducing species which humans made extinct."

MTorrice writes "Scientists have developed a way to convert lipids from sewage sludge into biodiesel. The low cost and high yield of the sludge process may make it economically feasible as a source of biofuel, the researchers say. Today, biofuel producers use lipids in vegetable oils to derive biodiesel, a mixture of fatty-acid-like molecules. Biodiesel is compatible with existing diesel engines, burns with less pollution than petroleum-derived diesel does, and comes from renewable resources. But current biodiesel feedstocks are expensive, limiting the fuel's widespread use. The researchers from South Korea found that sewage sludge, the semisolid material left over from wastewater treatment, can yield 2,200 times more lipids than soybeans and costs 96% less to process. To turn the sludge lipids into biodiesel, the researchers heated them with methanol."

An anonymous reader writes "Australian researchers implanted a bionic eye with 24 electrodes in Ms Dianne Ashworth, a 54-year-old who had limited vision due to a inherited condition called retinitis pigmentosa. The implant has allowed her to see flashes of light and shapes when researchers deliver electrical pulses to the device. From the article: 'This early prototype consists of a retinal implant with 24 electrodes. A small lead wire extends from the back of the eye to a connector behind the ear. An external system is connected to this unit in the laboratory, allowing researchers to stimulate the implant in a controlled manner in order to study the flashes of light. Feedback from Ms Ashworth will allow researchers to develop a vision processor so that images can be built using flashes of light. This early prototype does not incorporate an external camera – yet. This is planned for the next stage of development and testing.'"

waderoush writes "The San Diego Zoo has built a world famous reputation as a tourist destination, for helping to rescue the California Condor, and maybe (if you're old enough) for Joan Embery's appearances with Johnny Carson. Now the zoo is using its expertise to drive innovation by establishing a new 'Centre for Bioinspiration.' While the Anglicized spelling of 'center' might seem pretentious, the zoo has a down-to-earth goal of innovating through the emerging field of biomimicry, which is exemplified by Qualcomm's Mirasol display technology (the displays generate colors using the same type of interference between light waves that causes iridescence in butterfly wings). The center includes an incubator for developing new bio-inspired products and technologies, where ideas would be advanced to a proof of concept or working model, and then licensed. The incubator also intends to help develop bio-inspired ideas from outside the zoo."

MrSeb writes "Bioengineers at Harvard University have created the first examples of cyborg tissue: Neurons, heart cells, muscle, and blood vessels that are interwoven by nanowires and transistors. These cyborg tissues are half living cells, half electronics. As far as the cells are concerned, they're just normal cells that behave normally — but the electronic side actually acts as a sensor network, allowing a computer to interface directly with the cells. In the case of cyborg heart tissue, the researchers have already used the embedded nanowires to measure the contractions (heart rate) of the cells. So far, the researchers have only used the nanoelectric scaffolds to read data from the cells — but according to lead researcher Charles Lieber, the next step is to find a way of talking to the individual cells, to 'wire up tissue and communicate with it in the same way a biological system does.' Suffice it to say, if you can use a digital computer to read and write data to your body's cells, there are some awesome applications."

An anonymous reader writes "A forensic test that has been developed to help police nab perpetrators of crimes can predict a suspect's eye color, hair color, and ethnic origin. The test's ability and the science behind it has been outlined in Forensic Science International: Genetics (abstract). Developed by Susan Walsh and other researchers from the Netherlands, Greece, and Poland, the test uses phenotypes from DNA to ... predict a suspect's appearance using 'low amounts of template DNA, as well as degraded DNA,' which means that the DNA does not need to be perfect in order for the system to read it."

Hugh Pickens writes "Since 1900, the life expectancy of Americans, driven by improved hygiene, nutrition, and new medical discoveries and interventions, has jumped from 47 years to almost 80. Now, scientists studying the intricacies of DNA and other molecular bio-dynamics may be poised to offer even more dramatic boosts to longevity. But there is one very basic question that is seldom asked, according to David Ewing Duncan: How long do you want to live? 'Over the past three years I have posed this query to nearly 30,000 people at the start of talks and lectures on future trends in bioscience, taking an informal poll as a show of hands,' writes Duncan. 'To make it easier to tabulate responses I provided four possible answers: 80 years, currently the average life span in the West; 120 years, close to the maximum anyone has lived; 150 years, which would require a biotech breakthrough; and forever, which rejects the idea that life span has to have any limit at all.' The results: some 60 percent opted for a life span of 80 years. Another 30 percent chose 120 years, and almost 10 percent chose 150 years. Less than 1 percent embraced the idea that people might avoid death altogether (PDF). Overwhelmingly, the reason given was that people didn't want to be old and infirm any longer than they had to be, even if a pill allowed them to delay the inevitable. Others were concerned about issues like boredom, the cost of paying for a longer life, and the impact of so many extra people on planetary resources and on the environment. But wouldn't long life allow people like Albert Einstein to accomplish more and try new things? That's assuming that Einstein would want to live that long. As he lay dying of an abdominal aortic aneurysm in 1955, Einstein refused surgery, saying: 'It is tasteless to prolong life artificially. I have done my share, it is time to go. I will do it elegantly.'"

An anonymous reader writes "A team of engineers from Oregon State University has developed a breakthrough microbial fuel cell that is capable of generating 10 to 50 times more electricity from waste than other MFCs. The team hopes that their innovation will enable waste treatment plants to not only power themselves, but also sell excess electricity back to the grid. 'If this technology works on a commercial-scale the way we believe it will, the treatment of wastewater could be a huge energy producer, not a huge energy cost,' said associate professor Hong Liu. 'This could have an impact around the world, save a great deal of money, provide better water treatment and promote energy sustainability.'"

ananyo writes "In the 1930s, the pioneering geneticist J. B. S. Haldane noticed a peculiar inheritance pattern in families with long histories of haemophilia. The faulty mutation responsible for the blood-clotting disorder tended to arise on the X chromosomes that fathers passed to their daughters, rather than on those that mothers passed down. Haldane subsequently proposed that children inherit more mutations from their fathers than their mothers, although he acknowledged that 'it is difficult to see how this could be proved or disproved for many years to come.' That year has finally arrived: whole-genome sequencing of dozens of Icelandic families has at last provided the evidence that eluded Haldane. Moreover, the study, published in Nature, finds that the age at which a father sires children determines how many mutations those offspring inherit. By starting families in their thirties, forties and beyond, men could be increasing the chances that their children will develop autism, schizophrenia and other diseases often linked to new mutations (abstract)."

ananyo writes "Chemists have turned red blood cells into long lived sensors that could be put back into circulation to monitor the make up of patients' blood in real time. Many patients require monitoring of their blood, such as diabetics. But extracting blood is both invasive and provides only a one-off measurement. At the American Chemical Society meeting in Philadelphia, Xiaole Shao explained how her team has built sensors that may one day allow both non-invasive and long-term monitoring of crucial aspects of blood chemistry. Shao, a chemist at the University of Missouri-Columbia, and her colleagues exploited the fact that near-infrared light will penetrate skin. This means it can trigger florescent molecules that are circulating in the blood, and this florescence can be picked up by an external monitoring device. If the molecule's florescence changes in response to chemical conditions, these changes can also be detected, and you have a sensor. But florescent dyes can be toxic, and they don't last long in the body, as they are quickly filtered out. To avoid the problem, the researchers encapsulated the sensors in red blood cells. The team next plans to inject the sensors into rats."

ananyo writes "Developing oral contraceptives for men has not gone as swiftly as researchers imagined in the early 1970s; they suggested at the time that a 'male pill' was not far off. But researchers now report a new way to make male mice temporarily infertile. Although the treatment is not ready for human use, the method avoids some of the pitfalls of earlier attempts. The technique appears to have a much more specific action than previous methods: it impairs sperm production by blocking a protein called BRDT. This protein was singled out as a potential therapeutic target five years ago because it only occurs in the testes, where it is required for the division of sperm cells. If the approach proves safe in humans, it would be an improvement over hormone-based methods of male contraception, which are not completely effective and cause side effects such as mood swings, acne and a loss of libido (abstract). On the downside, however, the compound 'shrank the mice's testes.'"