MTorrice (2611475) writes "Despite cocaine's undeniable destructiveness, there are no antidotes for overdoses or medications to fight addiction that directly neutralize cocaine's powerful effects. A natural bacterial enzyme, cocaine esterase, could help by chopping up cocaine in the bloodstream. But the enzyme is unstable in the body, losing activity too quickly to be a viable treatment. Now, using computational design, researchers tweaked the enzyme (full paper, PDF) to simultaneously increase stability and catalytic efficiency. Mice injected with the engineered enzyme survive daily lethal doses of cocaine for an average of 94 hours."

realized writes: "A man with almost no hair on his body has grown a full head of it after a novel treatment by doctors at Yale University. The patient had previously been diagnosed with both alopecia universalis, a disease that results in loss of all body hair, and plaque psoriasis, a condition characterized by scaly red areas of skin. The only hair on his body was within the psoriasis plaques on his head. He was referred to Yale Dermatology for treatment of the psoriasis. The alopecia universalis had never been treated.

After two months on tofacitinib [an FDA-approved arthritis drug] at 10 mg daily, the patient's psoriasis showed some improvement, and the man had grown scalp and facial hair — the first hair he'd grown there in seven years. After three more months of therapy at 15 mg daily, the patient had completely regrown scalp hair and also had clearly visible eyebrows, eyelashes, and facial hair, as well as armpit and other hair, the doctors said."

Modular Science is something Tim Lord spotted at last month's O'Reilly Solid Conference in San Francisco. Its founder, Peter Sand, has a Ph.D. in Computer Science from MIT. He's scheduled to speak at this year's OSCON, and his speaker blurb for that conference says, "He is the founder of ManyLabs, a nonprofit focused on teaching math and science using sensors and simulations. Peter also founded Modular Science, a company working on hardware and software tools for science labs. He has given talks at Science Hack Day, Launch Edu, and multiple academic conferences, including SIGGRAPH." And now he's also been interviewed on Slashdot. Note that there are plenty of lab automation systems out there. Peter is working on one that is not only "an order of magnitude cheaper" than similar devices, but is also easy to modify and expand. It's the sort of system that would fit well not just in a college-level lab, but in a high school lab or a local makerspace. (Alternate Video Link)

Rambo Tribble writes Researchers in Britain are reporting that they have found a way to prevent bacteria from forming the "wall" that prevents antibiotics from attacking them. “It is a very significant breakthrough,” said Professor Changjiang Dong, from the University of East Anglia's (UAE) Norwich Medical School. “This is really important because drug-resistant bacteria is a global health problem. Many current antibiotics are becoming useless, causing hundreds of thousands of deaths each year. Many bacteria build up an outer defence which is important for their survival and drug resistance. We have found a way to stop that happening," he added. This research provides the platform for urgently-needed new generation drugs.

schwit1 (797399) writes "A super-enriched genetically engineered banana will soon go through its first human trial, which will test its effect on vitamin A levels, Australian researchers said Monday. The project plans to have the special banana varieties — enriched with alpha and beta carotene which the body converts to vitamin A — growing in Uganda by 2020. The bananas are now being sent to the United States, and it is expected that the six-week trial measuring how well they lift vitamin A levels in humans will begin soon."

think_nix (1467471) writes The EU Parliament is paving the way for EU Nation States to decide on banning or allowing GMO foods within their respective territories. An further article at Der Spiegel (German) (Google translation) quotes the German Health Minister's claim that if countries cannot specifically, scientifically argue for a ban, this would allow GMO companies to initiate legal actions against the banning ruling states. Furthermore it was noted, given EU Parliaments current stance on not reintroducing border and customs controls between member states, this will make checks and controls of GMO foods between member states even more difficult.

New submitter meghan elizabeth (3689911) writes Why stop at just mimicking biology when you can biomanufacture technologically improved humans? 3D-printed enhanced "superorgans"—or artificial ones that don't exist in nature—could be engineered to perform specific functions beyond what exists in nature, like treating disease. Already, a bioprinted artificial pancreas that can regulate glucose levels in diabetes patients is being developed. Bioprinting could also be used to create an enhanced organ that can generate electricity to power electronic implants, like pacemakers.

sciencehabit (1205606) writes Shutting down the research center at the heart of an unfolding scientific scandal may be necessary to prevent a recurrence of research misconduct, according to a report released at a press conference in Tokyo today. A committee reviewing conduct at the RIKEN Center for Developmental Biology (CDB) in Kobe, Japan, found lax oversight and a failure on the part of senior authors of two papers in Nature outlining a surprisingly simple way of reprogramming mature cells into stem cells. The committee surmised that a drive to produce groundbreaking results led to publishing results prematurely. "It seems that RIKEN CDB had a strong desire to produce major breakthrough results that would surpass iPS cell research," the report concludes, referring to another type of pluripotent stem cell. "One of our conclusions is that the CDB organization is part of the problem," said committee chair Teruo Kishi Kishi. He recommends a complete overhaul of CDB, including perhaps restructuring it into a new institute. "This has to be more than just changing the nameplate."

First time accepted submitter afeeney (719690) writes 'The Centre for Art and Media in Karlsruhe, Germany, is displaying an ear grown from DNA contributed by a relative of artist Vincent Van Gogh. The Center said artist Diemut Strebe made the replica using living cells from Lieuwe van Gogh, the great-great-grandson of Vincent’s brother Theo. Using a 3D-printer, the cells were shaped to resemble the ear that Vincent van Gogh is said to have cut off during a psychotic episode in 1888. “I use science basically like a type of brush, like Vincent used paint,” Strebe told The Associated Press. Historians argue about whether Van Gogh cut off his own ear and if so, why, but it remains one of the most famous acts of self-mutilation in the Western world.'

sciencehabit (1205606) writes "After several months of fiercely defending her discovery of a new, simple way to create pluripotent stem cells, Haruko Obokata of the RIKEN Center for Developmental Biology in Kobe, Japan, has agreed to retract the two Nature papers that reported her work. Satoru Kagaya, head of public relations for RIKEN, headquartered in Wako near Tokyo, confirmed press reports today that Obokata had finally agreed to retract both papers. He said the institute would be notifying Nature and that the decision to formally retract the papers would be up to the journal."

Jason Koebler (3528235) writes "Adam Steltzner, the lead engineer on the NASA JPL's Curiosity rover mission, believes that to send humans to distant planets, we may need to do one of two things: look for ways to game space-time—traveling through wormholes and whatnot—or rethink the fundamental idea of 'ourselves.' 'Our best bet for space exploration could be printing humans, organically, on another planet,' said Steltzner."

cablepokerface writes "We've had a significant family catastrophe last weekend. My sister-in-law (my wife's sister) is 28 years old and was 30 weeks pregnant till last Saturday. She also had a tumor — it was a benign, slow growing tumor close to her brain-stem. Naturally we were very worried about that condition, but several neurologists assessed the situation earlier and found the tumor to be a problem, but not big enough for her to require immediate surgery, so we decided to give the baby more time. She was symptomatic, but it was primarily pain in her neck area and that was controlled with acceptable levels of morphine.

Then, last Saturday, our lives changed. Probably forever. In the hospital, where she was admitted earlier that week to keep an eye on the baby, the tumor ruptured a small vessel and started leaking blood into the tumor, which swelled up to twice its size. Then she, effectively, had a stroke from the excess blood in the brain stem. In a hurry, the baby was born through C-section (30 weeks and it's a boy — he's doing fine). Saturday night she had complex brain surgery, which lasted nine hours. They removed the blood and tumor that was pressing on the brain.

Last Sunday/Monday they slowly tried to wake her up. The CT scan shows all higher brain functions to work, but a small part of the brain stem shows no activity. She is locked-in, which is a terrible thing to witness since she has virtually no control of any part of her body. She can't breathe on her own, and the only things she can move, ever so slightly, are her lips, eyelids and eyes. And even that's not very steady. Blinking her eyes to answer questions tires her out enormously, as she seems to have to work hard to control those. The crowd on Slashdot is a group of people who have in-depth knowledge of a wide range of topics. I'm certainly not asking for pity here, but maybe you can help me with the following questions: Does anyone have any ideas on how to communicate better with her? Is there technology that could help? Like brain-wave readers or something? Does anyone have any ideas I haven't thought of regarding communication with her, or maybe even experience with it?"

An anonymous reader writes "A biotech start-up from Massachusetts has an unusual product: a bottle full of bacteria you're supposed to spray onto your face. The bacteria is Nitrosomonas eutropha, and it's generally harmless. Its main use is that it oxidizes ammonia, and the start-up's researchers suspect it used to commonly live on human skin before we began washing it away with soaps and other cleaners. Such bacteria are an area of heavy research in biology right now. Scientists know that the gut microbiome is important to proper digestion, and they're trying to figure out if an external microbiome can be similarly beneficial to skin. A journalist for the NY Times volunteered to test the product, which involved four straight weeks of no showers, no soap, no shampoo, and no deodorant. The sprayed-on bacteria quickly colonized her skin, along with other known types of bacteria — and hundreds of unknown (but apparently harmless) strains. She reported improvements to her skin and complexion, and described how the bacteria worked to curtail (but not eliminate) the body odor caused by not washing. At the end of the experiment, all of the N. eutropha vanished within three showers."

First time accepted submitter VT-802-Software (3663479) writes "A bipartisan proposal to curb patent trolls was shelved by the chairman of the Senate Judiciary Committee, Patrick Leahy (D-Vt.) Wednesday. 'Supporters of the compromise accuse trial lawyers, universities, pharmaceutical companies and biotech companies for foiling the plan at the eleventh hour. As late as Tuesday, the University of Vermont and a biotech coalition each sent letters to Leahy opposing the legislation. "We believe the measures in the legislation go far beyond what is necessary or desirable to combat abusive patent litigation, and would do serious damage to the patent system," reads one of the letters. "Many of the provisions would have the effect of treating every patent holder as a patent troll."'"

An anonymous reader writes "There is certainly no shortage of stories about AI systems that include the saying, 'like the brain'. This article takes a critical look at those claims and just what 'like the brain' means. The conclusion: while not a lie, the catch-phrase isn't very informative and may not mean much given our lack of understanding on how the brain works. From the article: 'Surely these claims can't all be true? After all, the brain is an incredibly complex and specific structure, forged in the relentless pressure of millions of years of evolution to be organized just so. We may have a lot of outstanding questions about how it works, but work a certain way it must. But here's the thing: this "like the brain" label usually isn't a lie — it's just not very informative. There are many ways a system can be like the brain, but only a fraction of these will prove important. We know so much that is true about the brain, but the defining issue in theoretical neuroscience today is, simply put, we don't know what matters when it comes to understanding how the brain computes. The debate is wide open, with plausible guesses about the fundamental unit, ranging from quantum phenomena all the way to regions spanning millimeters of brain tissue.'"

KentuckyFC (1144503) writes "The study of proteins has become one of the hottest topics in science in the last 20 years, and not just for biologists. Researchers have been measuring the electrical properties of proteins for some time, discovering that some of them act like switches in certain circumstances. That's potentially useful but without a robust theoretical model of how these properties arise, nobody has been able to incorporate proteins into real devices. Now electronics engineers have developed the first model that reliably describes the real electrical behaviour of proteins and how it changes when they bond to other molecules. It even predicts the behaviour in new situations. That should make it possible to use proteins in the same way as other electronic components such as transistors, diodes and so on. That's leading to an entirely new field of science called proteotronics in which proteins work seamlessly with other components in electronic devices. First up, an electronic nose based on the olfactory receptor OR-17, a protein found in rats, which behaves like an electronic switch when it detects the presence of aldehydes such as octanal."

Taffykay (2047384) writes "Tech giant Fujitsu has opened an organic lettuce farm in Japan's Fukushima prefecture. Blending agriculture, technology, and medicine in a former microchip factory, the company has developed a new variety of organic lettuce that is not only lower in potassium and nitrates than standard varieties, but is also radiation-free."

sciencehabit (1205606) writes "Every day, our cells manufacture small amounts of a molecule that, in higher doses, might be the key to leading a longer, healthier life. A team of researchers has found that this molecule boosts the lifespan of worms by more than 50%, raising the possibility that it will increase human longevity. Dietary supplements that contain the molecule and allegedly build muscle are already on the market. The study drops a barbell on their use, however, by suggesting that the molecule may actually thwart muscle growth."

the_newsbeagle writes "People who are into the quantified health trend can already measure and chart a wide variety of metrics — steps taken, calories burned, heart rate, blood pressure, sleep patterns, etc can all be tracked using new gadgets. Now a new device called Cue lets people track their biochemical stats, too. Cue offers five DIY lab tests, automates the testing procedure, and sends the results to the user's smartphone. It lets guys check their testosterone levels, ladies check their fertility status, and also offers tests for the flu virus, vitamin D levels, and an inflammation-marker protein. Apparently more tests are expected down the line."

samzenpus (5) writes "Last week you had the chance to ask biologist Stewart Brand about his books, his life, and his Revive & Restore project, which aims to to bring back extinct species and provide genetic rescue for those that are endangered. Below you'll find his answers to your questions."