Biotech

Japanese Stem Cell Debacle Could Bring Down Entire Center 52

sciencehabit (1205606) writes Shutting down the research center at the heart of an unfolding scientific scandal may be necessary to prevent a recurrence of research misconduct, according to a report released at a press conference in Tokyo today. A committee reviewing conduct at the RIKEN Center for Developmental Biology (CDB) in Kobe, Japan, found lax oversight and a failure on the part of senior authors of two papers in Nature outlining a surprisingly simple way of reprogramming mature cells into stem cells. The committee surmised that a drive to produce groundbreaking results led to publishing results prematurely. "It seems that RIKEN CDB had a strong desire to produce major breakthrough results that would surpass iPS cell research," the report concludes, referring to another type of pluripotent stem cell. "One of our conclusions is that the CDB organization is part of the problem," said committee chair Teruo Kishi Kishi. He recommends a complete overhaul of CDB, including perhaps restructuring it into a new institute. "This has to be more than just changing the nameplate."
Biotech

Ear Grown From Van Gogh DNA On Display 64

First time accepted submitter afeeney (719690) writes 'The Centre for Art and Media in Karlsruhe, Germany, is displaying an ear grown from DNA contributed by a relative of artist Vincent Van Gogh. The Center said artist Diemut Strebe made the replica using living cells from Lieuwe van Gogh, the great-great-grandson of Vincent’s brother Theo. Using a 3D-printer, the cells were shaped to resemble the ear that Vincent van Gogh is said to have cut off during a psychotic episode in 1888. “I use science basically like a type of brush, like Vincent used paint,” Strebe told The Associated Press. Historians argue about whether Van Gogh cut off his own ear and if so, why, but it remains one of the most famous acts of self-mutilation in the Western world.'
Biotech

Key Researcher Agrees To Retract Disputed Stem Cell Papers 61

sciencehabit (1205606) writes "After several months of fiercely defending her discovery of a new, simple way to create pluripotent stem cells, Haruko Obokata of the RIKEN Center for Developmental Biology in Kobe, Japan, has agreed to retract the two Nature papers that reported her work. Satoru Kagaya, head of public relations for RIKEN, headquartered in Wako near Tokyo, confirmed press reports today that Obokata had finally agreed to retract both papers. He said the institute would be notifying Nature and that the decision to formally retract the papers would be up to the journal."
Biotech

'Curiosity' Lead Engineer Suggests Printing Humans On Other Planets 323

Jason Koebler (3528235) writes "Adam Steltzner, the lead engineer on the NASA JPL's Curiosity rover mission, believes that to send humans to distant planets, we may need to do one of two things: look for ways to game space-time—traveling through wormholes and whatnot—or rethink the fundamental idea of 'ourselves.' 'Our best bet for space exploration could be printing humans, organically, on another planet,' said Steltzner."
Communications

Ask Slashdot: Communication With Locked-in Syndrome Patient? 552

cablepokerface writes "We've had a significant family catastrophe last weekend. My sister-in-law (my wife's sister) is 28 years old and was 30 weeks pregnant till last Saturday. She also had a tumor — it was a benign, slow growing tumor close to her brain-stem. Naturally we were very worried about that condition, but several neurologists assessed the situation earlier and found the tumor to be a problem, but not big enough for her to require immediate surgery, so we decided to give the baby more time. She was symptomatic, but it was primarily pain in her neck area and that was controlled with acceptable levels of morphine.

Then, last Saturday, our lives changed. Probably forever. In the hospital, where she was admitted earlier that week to keep an eye on the baby, the tumor ruptured a small vessel and started leaking blood into the tumor, which swelled up to twice its size. Then she, effectively, had a stroke from the excess blood in the brain stem. In a hurry, the baby was born through C-section (30 weeks and it's a boy — he's doing fine). Saturday night she had complex brain surgery, which lasted nine hours. They removed the blood and tumor that was pressing on the brain.

Last Sunday/Monday they slowly tried to wake her up. The CT scan shows all higher brain functions to work, but a small part of the brain stem shows no activity. She is locked-in, which is a terrible thing to witness since she has virtually no control of any part of her body. She can't breathe on her own, and the only things she can move, ever so slightly, are her lips, eyelids and eyes. And even that's not very steady. Blinking her eyes to answer questions tires her out enormously, as she seems to have to work hard to control those. The crowd on Slashdot is a group of people who have in-depth knowledge of a wide range of topics. I'm certainly not asking for pity here, but maybe you can help me with the following questions: Does anyone have any ideas on how to communicate better with her? Is there technology that could help? Like brain-wave readers or something? Does anyone have any ideas I haven't thought of regarding communication with her, or maybe even experience with it?"
Biotech

Four Weeks Without Soap Or Shampoo 250

An anonymous reader writes "A biotech start-up from Massachusetts has an unusual product: a bottle full of bacteria you're supposed to spray onto your face. The bacteria is Nitrosomonas eutropha, and it's generally harmless. Its main use is that it oxidizes ammonia, and the start-up's researchers suspect it used to commonly live on human skin before we began washing it away with soaps and other cleaners. Such bacteria are an area of heavy research in biology right now. Scientists know that the gut microbiome is important to proper digestion, and they're trying to figure out if an external microbiome can be similarly beneficial to skin. A journalist for the NY Times volunteered to test the product, which involved four straight weeks of no showers, no soap, no shampoo, and no deodorant. The sprayed-on bacteria quickly colonized her skin, along with other known types of bacteria — and hundreds of unknown (but apparently harmless) strains. She reported improvements to her skin and complexion, and described how the bacteria worked to curtail (but not eliminate) the body odor caused by not washing. At the end of the experiment, all of the N. eutropha vanished within three showers."
Patents

Who Helped Kill Patent Troll Reform In the Senate 157

First time accepted submitter VT-802-Software (3663479) writes "A bipartisan proposal to curb patent trolls was shelved by the chairman of the Senate Judiciary Committee, Patrick Leahy (D-Vt.) Wednesday. 'Supporters of the compromise accuse trial lawyers, universities, pharmaceutical companies and biotech companies for foiling the plan at the eleventh hour. As late as Tuesday, the University of Vermont and a biotech coalition each sent letters to Leahy opposing the legislation. "We believe the measures in the legislation go far beyond what is necessary or desirable to combat abusive patent litigation, and would do serious damage to the patent system," reads one of the letters. "Many of the provisions would have the effect of treating every patent holder as a patent troll."'"
Biotech

Why Not Every New "Like the Brain" System Will Prove Important 47

An anonymous reader writes "There is certainly no shortage of stories about AI systems that include the saying, 'like the brain'. This article takes a critical look at those claims and just what 'like the brain' means. The conclusion: while not a lie, the catch-phrase isn't very informative and may not mean much given our lack of understanding on how the brain works. From the article: 'Surely these claims can't all be true? After all, the brain is an incredibly complex and specific structure, forged in the relentless pressure of millions of years of evolution to be organized just so. We may have a lot of outstanding questions about how it works, but work a certain way it must. But here's the thing: this "like the brain" label usually isn't a lie — it's just not very informative. There are many ways a system can be like the brain, but only a fraction of these will prove important. We know so much that is true about the brain, but the defining issue in theoretical neuroscience today is, simply put, we don't know what matters when it comes to understanding how the brain computes. The debate is wide open, with plausible guesses about the fundamental unit, ranging from quantum phenomena all the way to regions spanning millimeters of brain tissue.'"
Biotech

How the Emerging Science of Proteotronics Will Change Electronics 29

KentuckyFC (1144503) writes "The study of proteins has become one of the hottest topics in science in the last 20 years, and not just for biologists. Researchers have been measuring the electrical properties of proteins for some time, discovering that some of them act like switches in certain circumstances. That's potentially useful but without a robust theoretical model of how these properties arise, nobody has been able to incorporate proteins into real devices. Now electronics engineers have developed the first model that reliably describes the real electrical behaviour of proteins and how it changes when they bond to other molecules. It even predicts the behaviour in new situations. That should make it possible to use proteins in the same way as other electronic components such as transistors, diodes and so on. That's leading to an entirely new field of science called proteotronics in which proteins work seamlessly with other components in electronic devices. First up, an electronic nose based on the olfactory receptor OR-17, a protein found in rats, which behaves like an electronic switch when it detects the presence of aldehydes such as octanal."
Earth

Fujitsu Is Growing Radiation-Free Lettuce In Japan's Fukushima Prefecture 146

Taffykay (2047384) writes "Tech giant Fujitsu has opened an organic lettuce farm in Japan's Fukushima prefecture. Blending agriculture, technology, and medicine in a former microchip factory, the company has developed a new variety of organic lettuce that is not only lower in potassium and nitrates than standard varieties, but is also radiation-free."
Biotech

Cellular Compound May Increase Lifespan Without the Need For Strict Dieting 66

sciencehabit (1205606) writes "Every day, our cells manufacture small amounts of a molecule that, in higher doses, might be the key to leading a longer, healthier life. A team of researchers has found that this molecule boosts the lifespan of worms by more than 50%, raising the possibility that it will increase human longevity. Dietary supplements that contain the molecule and allegedly build muscle are already on the market. The study drops a barbell on their use, however, by suggesting that the molecule may actually thwart muscle growth."
Biotech

DIY Lab Tests Getting More Capable 85

the_newsbeagle writes "People who are into the quantified health trend can already measure and chart a wide variety of metrics — steps taken, calories burned, heart rate, blood pressure, sleep patterns, etc can all be tracked using new gadgets. Now a new device called Cue lets people track their biochemical stats, too. Cue offers five DIY lab tests, automates the testing procedure, and sends the results to the user's smartphone. It lets guys check their testosterone levels, ladies check their fertility status, and also offers tests for the flu virus, vitamin D levels, and an inflammation-marker protein. Apparently more tests are expected down the line."
Earth

Harvard Study Links Neonicotinoid Pesticide To Colony Collapse Disorder 217

walterbyrd (182728) writes in with news about a new study from Harvard School of Public Health that links two widely used neonicotinoids to Colony Collapse Disorder. "Colony Collapse Disorder (CCD), or the widespread population loss of honeybees, may have been caused by the use of neonicotinoids, according to a new study out of Harvard University. Neonicotinoids are a class of pesticides, chemically similar to nicotine. They were first developed for agricultural use in the 1980's by petroleum giant Shell. The pesticides were refined by Bayer the following decade. Two of these chemicals are now believed to be the cause of CCD, according to the new study from the School of Public Health at the university. This study replicated their own research performed in 2012."
Biotech

Luke Prosthetic Arm Approved By FDA 59

necro81 writes: "The FDA today approved the Luke prosthetic arm for sale. The Luke Arm, created by Dean Kamen's DEKA R&D Corp., was a project initiated by DARPA to develop a prosthetic arm for wounded warriors more advanced than those previously available. The Arm can be configured for below-the-elbow, above-the-elbow, and shoulder-level amputees. The full arm has 10 powered degrees of freedom and has the look and weight of the arm it replaces. Through trials by DEKA and the Dept. of Veterans Affairs, the Arm has been used by dozens of amputees for a total of many thousands of hours. Commercialization is still pending."
Biotech

Scientists Create Bacteria With Expanded DNA Code 85

perryizgr8 (1370173) writes "Biologists have managed to create a bacteria with DNA made of the usual A-T, C-G plus an artificial third base pair, thus encoding more data in DNA. From the article: 'The scientists behind the work at the Scripps Research Institute have already formed a company to try to use the technique to develop new antibiotics, vaccines and other products, though a lot more work needs to be done before this is practical. The work also gives some support to the concept that life can exist elsewhere in the universe using genetics different from those on Earth. “This is the first time that you have had a living cell manage an alien genetic alphabet,” said Steven A. Benner, a researcher in the field at the Foundation for Applied Molecular Evolution in Gainesville, Fla., who was not involved in the new work.'"
Biotech

Single Gene Can Boost IQ By Six Points 199

ananyo (2519492) writes "People are living longer, which is good. But old age often brings a decline in mental faculties and many researchers are looking for ways to slow or halt such decline. One group doing so is led by Dena Dubal of the University of California, San Francisco, and Lennart Mucke of the Gladstone Institutes, also in San Francisco. Dr Dubal and Dr Mucke have been studying the role in aging of klotho, a protein encoded by a gene called KL. A particular version of this gene, KL-VS, promotes longevity. One way it does so is by reducing age-related heart disease. Dr Dubal and Dr Mucke wondered if it might have similar powers over age-related cognitive decline. What they found was startling. KL-VS did not curb decline, but it did boost cognitive faculties regardless of a person's age by the equivalent of about six IQ points. If this result, just published in Cell Reports, is confirmed, KL-VS will be the most important genetic agent of non-pathological variation in intelligence yet discovered."
Biotech

Controlling Fear By Modifying DNA 105

An anonymous reader writes "The fear of flying or of skittering spiders can mean more than just a momentary increase in heart rate and a pair of sweaty palms. A hard-core phobia can lead to crippling anxiety. Now an international team of researchers says it believes it has found a way to silence the gene that feeds phobic fear via a novel mechanism of gene regulation associated with fear extinction. The notion appears to be that phobias arise from experiences that have left an outsized imprint on gene expression, and that undoing this can undo the anxiety itself. The study was published this month (abstract) in the Proceedings of the National Academy of Sciences."
Earth

Scientists Race To Develop Livestock That Can Survive Climate Change 291

Hugh Pickens DOT Com (2995471) writes "Evan Halper writes in the LA Times that with efforts to reduce carbon emissions lagging, researchers, backed by millions of dollars from the federal government, are looking for ways to protect key industries from the impact of climate change by racing to develop new breeds of farm animals that can stand up to the hazards of global warming. ""We are dealing with the challenge of difficult weather conditions at the same time we have to massively increase food production" to accommodate larger populations and a growing demand for meat, says Agriculture Secretary Tom Vilsack. For example a team of researchers is trying to map the genetic code of bizarre-looking African naked-neck chickens to see if their ability to withstand heat can be bred into flocks of US broilers. "The game is changing since the climate is changing," says Carl Schmidt. "We have to start now to anticipate what changes we have to make in order to feed 9 billion people," citing global-population estimates for 2050." (More below.)
Biotech

Male Scent Molecules May Be Compromising Biomedical Research 274

sciencehabit (1205606) writes "Scientists have found that mice feel 36% less pain when a male researcher is in the room, versus a female researcher. The rodents are also less stressed out. The effect appears to be due to scent molecules that male mammals (including humans, dogs, and cats) have been emitting for eons. The finding could help explain why some labs have trouble replicating the results of others, and it could cause a reevaluation of decades of animal experiments: everything from the effectiveness of experimental drugs to the ability of monkeys to do math. Male odor could even influence human clinical trials."

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